Light-Triggered Nitric Oxide Releasing PVA/Ɣ-PGA Electrospun Wound Dressings
Year: 2026
Type: article
Abstract: Antimicrobial blue light (aBL) (400-470 nm) and nitric oxide (NO) each exhibit exceptional antibacterial activity. However, aBL can be cytotoxic at bactericidal doses, while NO’s transient biological lifetime requires sustained release which can also damage host cells. This work attempts to create a combined system achieving photochemical NO release with high NO fluxes, enhancing antibacterial effects while reducing required NO donor concentrations and aBL energy densities. This approach is relevant for the treatment of chronic wounds where infection is a primary barrier to healing.
Source: UNC Libraries
DOI: 10.17615/3eth-qd50
Author: Landrum, Nolan
Institution: University of North Carolina at Chapel Hill
Language: English
Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7203929561
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