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Early Bilateral Symmetrical Putaminal Involvement in Subacute Sclerosing Panencephalitis: An Unusual Neuroimaging Pattern

Year: 2026

Type: article

Abstract: Subacute sclerosing panencephalitis (SSPE) classically shows parieto-occipital white matter changes on magnetic resonance imaging (MRI). We report an 11-year-old boy with prior measles infection presenting with neuroregression and myoclonus, with electroencephalography (EEG) showing periodic complexes. MRI revealed atypical symmetric putaminal diffusion restriction with frontal white matter changes. Diagnosis was confirmed by elevated cerebrospinal fluid anti-measles IgG. This case highlights an atypical imaging pattern of SSPE, emphasizing the importance of clinical and EEG correlation for early diagnosis.

Source: Journal of Pediatric Neurosciences

DOI: 10.4103/jpn.jpn_97_26

Authors: Roshwanth Arbujin, Ratan Gupta, Sameer Peer, Aakash Mahesan, Arvinder Wander

Institution: All India Institute of Medical Sciences

Language: English

Topic: Virology and Viral Diseases

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7204082645

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Cites: 18

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