Esophageal cancer-associated thoracic central venous obstruction type 2 which occurred during chemoradiotherapy
Year: 2026
Type: article
Study design: Case Report
Abstract: Thoracic central venous obstruction (TCVO) can cause facial and upper extremity edema and it is often associated with malignancies. We herein report a rare case of cervical esophageal squamous cell carcinoma complicated by TCVO type 2 during chemoradiotherapy. Approximately 1 week after starting 5-fluorouracil plus cisplatin with radiotherapy, the patient developed acute painful swelling of the left arm. Contrast-enhanced computed tomography revealed thrombosis of the left internal jugular vein with extrinsic compression of the ipsilateral subclavian vein by a cervical tumor. Symptoms improved after anticoagulation therapy while chemoradiotherapy was continued, although the improvement was likely multifactorial.
Source: Internal Medicine
Authors: Yoshiki Tokunaga, Kohei Hayashi, Rie Uehara, Amane Jubashi, Tomonori Araki, Takuya Honda, Hisamitsu Miyaaki
Institution: Nagasaki University
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7204086633