Nuclear mechanobiology: a brief history and five unresolved questions
Year: 2026
Type: article
Abstract: The nucleus has long been recognized as the repository of the cell’s genomic information, providing the blueprints for assembling the cell’s structures and carrying out its functions. Over the past...
Source: Nucleus
Institutions: Cornell University, Radboud University Nijmegen, Columbia University, Yale University, Texas A&M University, University of California, Los Angeles, University of California, Davis, University of Zurich, Biologie cellulaire et Cancer, Barcelona Institute of Science and Technology, Universitat de Barcelona, LMU Klinikum, Institut für Kardiovaskuläre Physiologie und Pathophysiologie, Ludwig-Maximilians-Universität München, Sanford Research, Genentech, Stanford University, Max Planck Institute for Molecular Biomedicine
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,993
Funders: David and Lucile Packard Foundation, Paul G. Allen Frontiers Group, Deutsche Forschungsgemeinschaft, Volkswagen Foundation, Fondation Leducq, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke
Awards: G1182948925, G273284403, The genetic and non-genetic responses of chromatin to force, Nuclear mechanics and mechanotransduction in muscular laminopathies, Biophysikalische Mechanismen der Dissemination von Toxoplasma gondii mittels migratorischer Immunzellen, PRIORITY: cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY, Nucleoskeleton-Cytoskeleton Connections and Cell Polarity in Aging, Mechanistic Basis of Cardiac Laminopathy, Cytoskeletal regulation of cardiomyocyte homeostasis in health and disease, Nuclear mechanobiology in confined migration, G9000002595, G9000015764, G9000232150, G9000267596, G9000298518, Mechanopriming for cell engineering, Using mouse models to dissect the roles of ZMPSTE24 and prelamin A in accelerated aging, Defining nuclear mechanisms for ultrarapid mechanically induced gene expression
OpenAlex ID: W7204102630