Work

Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA Pathway

Year: 2026

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-25-1047

Authors: Ziyue Z. Yang, Angelina S. Bortoletto, Mara G. Cardenas, Mason D. Bartels, Savannah Mwesigwa, Charlotte A. Le Roux, Caroline G. Snider, Man-Tzu Wang, Huihui Fan, Eric L. Van Nostrand, Frank McCormick, Ronald J. Parchem

Institutions: Baylor College of Medicine, Texas Medical Center, The University of Texas Health Science Center, Rice University, Rapt Therapeutics (United States), Frederick National Laboratory for Cancer Research, UCSF Helen Diller Family Comprehensive Cancer Center

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: V Foundation for Cancer Research, Cancer Prevention and Research Institute of Texas, Lustgarten Foundation, National Heart, Lung, and Blood Institute

Awards: Recruitment of First-Time, Tenure-Track Faculty Members, G4964878375, G5548077189, G9000847950

OpenAlex ID: W7204105905

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