Predictors of cardiac rehabilitation completion after acute myocardial infarction in young women: the French WAMIF Registry
Year: 2026
Type: article
Abstract: Aims Cardiac rehabilitation (CR) is a cornerstone of secondary prevention after acute myocardial infarction (AMI), yet its implementation remains suboptimal, particularly among women. Young women represent an understudied subgroup with distinct presentations and psychosocial vulnerabilities that may influence access to CR. We aimed to identify factors associated with CR completion within 1 year after AMI in young women. Methods and results This exploratory analysis was conducted within the prospective multicentre WAMIF cohort. Women aged <50 years with AMI and available data on CR participation were included. The primary endpoint was CR completion within 1 year. Baseline characteristics were compared according to CR status. Univariable and multivariable logistic regression were used to identify factors independently associated with CR completion. Among 305 young women, 182 (59.7%) completed CR within 1 year after AMI. Age, cardiovascular risk factors, socioeconomic deprivation (EPICES score >30), and prior cardiovascular disease were not significantly different between groups. In univariable analysis, coronary occlusion, ST-elevation myocardial infarction (STEMI), and cardiac arrest were positively associated with CR completion, whereas absence of revascularization and higher LVEF were negatively associated. In multivariable analysis, STEMI remained independently associated with higher odds of CR completion (adjusted odds ratio [aOR] 1.9, 95% confidence interval [CI] 1.1–3.1; P = 0.019), whereas absence of revascularization was independently associated with lower CR completion (aOR 0.4, 95% CI 0.2–0.8; P = 0.007). Conclusion In young women with AMI, this exploratory analysis showed that CR completion remained suboptimal and was mainly associated with index-event severity and management rather than baseline risk factor burden or social deprivation. Registration WAMIF NCT03073447.
Source: European Heart Journal Open
Authors: Pierre-Guillaume Piriou, Théodora Angoulvant, Claire Bouleti, Geneviève Jarry, Yves Cottin, Pascal Motreff, Stéphanie Marliere, Sabrina Uhry, Guillaume Cayla, Guillaume Leurent, Matthieu Godin, Emmanuelle Filippi Codaccioni, Grégoire Rangé, Hélène Eltchaninoff, Jules Mesnier, Martine Gilard, Stéphane Manzo-Silberman
Institutions: Centre National de la Recherche Scientifique, Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris, Institut du Thorax, Hôpital Bichat-Claude-Bernard, Nantes Université, Université de Tours, Membrane Signalling and Inflammation in reperfusion Injuries, Université de Poitiers, Centre Hospitalier Universitaire de Poitiers, Centre Hospitalier Universitaire Amiens-Picardie, CHU Dijon Bourgogne, Université Clermont Auvergne, Centre Hospitalier Universitaire de Clermont-Ferrand, Centre Hospitalier Universitaire de Grenoble, Université de Montpellier, Centre Hospitalier Universitaire de Nîmes, Laboratoire Traitement du Signal et de l'Image, Centre Hospitalier Universitaire de Rennes, Les Hôpitaux de Chartres, Université de Rouen Normandie, Sorbonne Université, Pitié-Salpêtrière Hospital
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,673
OpenAlex ID: W7204119595