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Late-onset central nervous system Toxoplasma gondii infection after CAR T-cell therapy

Year: 2026

Type: article

Abstract: Toxoplasmosis is a zoonosis caused by the protozoan Toxoplasma gondii, an obligate intracellular parasite with high global prevalence.1,2 While primary infection is asymptomatic or mild and self-limiting in healthy individuals, immunocompromised patients may develop life-

Source: Blood Immunology & Cellular Therapy

DOI: 10.1016/j.bict.2026.100084

Authors: Flavia Gava, Stephanie Smith, Sara K. Silbert, Alexandra Dreyzin, Juliane Gust, Joseph M. Rocco, Shipra Goel, Krzysztof Bochenek, Thomas C. Newton, Nirali N. Shah

Institutions: National Institutes of Health, National Cancer Institute, Center for Cancer Research, Inova Children's Hospital, University of Washington, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Toxoplasma gondii Research Studies

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,000

Funders: U.S. Department of Health and Human Services, Memorial Sloan-Kettering Cancer Center, National Institutes of Health, National Cancer Institute, NIH Clinical Center

Awards: G5895579807, Development of Novel Approaches to Optimize CAR T-cell Therapies for B-cell Malignancies

OpenAlex ID: W7204141395

FWCI:

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