Figure 4 from Co-Clinical Evaluation of Synthetic Vitamin D and Chemotherapy in Pancreatic Cancer by Integrated Imaging and Molecular Analyses
Year: 2026
Type: other
Abstract: Matrix collagen level in KPC tumors. Micrographs of Sirius red (SR) staining of the tumor and posttreatment matrix collagen level estimated by %SR positive are presented for treatment arms in the matched trial (A) and the chemo–stromal trial (B). Time course of MTR in matched treatment arms (top, C) and the chemo–stromal trial (bottom, C). Correlation between MTR and cell density of the tumor (D). Correlation between matrix collagen and MVD (E). Scale bars, 70 μm. Sample size: control (CNTRL), n = 15; Cal, n = 9; NGC + Cal + PD-L1, n = 9; NGC, n = 16; NGC + Cal, n = 15; and NGC + Losa, n = 22. **, P < 0.01; Mann–Whitney test with two-tailed P value (details in the “Statistical analysis” section). The representative H&E image shown for the control group is from the same control tumor specimen shown in Fig. 3 but corresponds to a different tumor region, as indicated by the boxed area in the thumbnail image.
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7204155045
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