Work

Biomarker Axes, Detection Limits, and Endotype Stability in CRS: Reply to Katkuri et al. and Hong

Year: 2026

Type: article

Abstract: We thank Katkuri et al. and Hong for their insightful letters responding to our study on the effects of appropriate medical therapy (AMT) for chronic rhinosinusitis [ 1-3 ].Both letters affirm the principal finding that AMT preferentially attenuates Type 2 (T2) and eosinophil-associated inflammatory signals alongside improvements in endoscopic, radiographic, and patient-reported outcomes, while raising important methodological and interpretative questions to which we are pleased to address.

Source: International Forum of Allergy & Rhinology

DOI: 10.1002/alr.70258

Authors: Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan

Institution: Northwestern University

Language: English

Topic: Sinusitis and nasal conditions

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7204200241

FWCI:

Cites: 5

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