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Rectal Gastrointestinal Stromal Tumor Poor Response to Imatinib: A Case Report

Year: 2026

Type: article

Abstract: A 63-year-old man presented with persistent constipation lasting 6.5 months. Digital rectal examination revealed a soft-tissue lesion near the anal verge without bleeding. Further evaluation identified a rectal mass. Treatment with imatinib for 6 months showed no significant response. The patient subsequently underwent surgical resection, with favorable short-term clinical outcomes.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.73395

Authors: Majid Einakchi, Alireza Samimi, Tooraj Zandbaf, Narges Mesbah

Institutions: Mashhad University of Medical Sciences, Islamic Azad University, Mashhad

Language: English

Topic: Gastrointestinal Tumor Research and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820