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Data and code associated with the publication: Reaction enhancement via product scavenging and phase separation-driven pathway canalization

Year: 2026

Type: dataset

Abstract: Simulation codes and raw data (gel images and microscope images) for the paper entitled “Reaction enhancement via product scavenging and phase separation-driven pathway canalization”. The repository serves researchers, primarily in the field of phase separation and nucleic acid chemistry, while also intersecting synthetic biology, systems chemistry, and biochemistry. It contains a Python simulation code for scavenger-assisted ribozyme kinetics to estimated cleaved product formation with an accelerated rate. Also, it includes MATLAB code to measure droplet sizes (radius) of biomolecular condensates obtained from epifluorescence or confocal microscopy. Another MATLAB code can be used to analyze gel band intensities.

Source: Research Data Repository, Duke University

DOI: 10.7281/t1arut0s

Authors: Kang, Byunghwa, Lee, Heonjoon, Kengmana, Eli, Yea, Jie Yi, Kim, Dong Woo, Schulman, Rebecca

Institution: Johns Hopkins University

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: U.S. Department of Defense, Alfred P. Sloan Foundation

Awards: G1813104318, G2245770924, G6697060577

OpenAlex ID: W7204211898

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