Sürdürülebi̇li̇r Sağlik Si̇stemleri̇nde Postbi̇yoti̇kleri̇n Rolü: Döngüsel Bi̇yoekonomi̇, Anti̇mi̇krobi̇yal Di̇renç Ve Gelecek Perspekti̇fleri̇
Year: 2026
Type: article
Abstract: The development of sustainable health systems requires environmentally responsible, resource-efficient and scientifically validated biotechnological solutions. This review evaluates the potential role of postbiotics, defined as preparations of inanimate microorganisms and/or their components that confer health benefits, in sustainable healthcare. Current evidence was examined in relation to sustainable production, circular bioeconomy, antimicrobial resistance, food and veterinary applications, industrial biotechnology and life-cycle assessment. Postbiotics may offer advantages in product stability, shelf life, quality standardization and logistics. Bacteriocins, organic acids and other microbial components may also support pathogen control, biofilm inhibition and antimicrobial stewardship. The valorization of agro-industrial side streams as fermentation substrates may contribute to circular production models. Nevertheless, direct life-cycle evidence demonstrating environmental superiority and robust clinical data remain limited. Comparative assessments should integrate efficacy, safety, energy and water use, greenhouse-gas emissions, production costs and end-of-life scenarios. Postbiotics are promising tools for sustainable health and circular bioeconomy; however, standardized manufacturing, chemical characterization, cost-effectiveness studies and high-quality clinical and field trials are required before broad implementation.
Source: DergiPark (Istanbul University)
Institution: İstanbul Nişantaşı Üniversitesi
Language: Turkish
Subfield: Food Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7204220058