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Apelin-13 drives VSMC proliferation and atherosclerosis through REEP5-dependent disruption of ER-mitochondria coupling and glycolytic shift

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Year: 2026
Type: article
Source: Life Sciences
DOI: 10.1016/j.lfs.2026.124643
Authors: Huimei Liu, Wei Chen, Hui Mao, Ruirui Lu, Xiaosi Zhou, Xueqian Ouyang, Sisi Fan, Xiaohui Huang, Xiaobo Hu, Yixuan Deng, Linxi Chen, Lanfang Li
Institution: University of South China
Language: English

Topic: Apelin-related biomedical research
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Key Project of Research and Development Plan of Hunan Province, Natural Science Foundation of Hunan Province, Hunan Provincial Innovation Foundation for Postgraduate
Awards: Elabela-32抑制线粒体铜离子超载及线粒体未折叠蛋白反应拮抗CuCl2诱导的血管内皮细胞衰老, G3547781590, Cyclic Apelin-12新型环肽拮抗Ang II和Apelin-13诱导VSMC增殖的分子机制, G4635882117, G6684243904, Cyclic Apelin-12新型环肽上调内质网膜蛋白REEP5促线粒体相关内质网膜MAMs形成拮抗Apelin-13/APJ诱导的VSMC增殖
OpenAlex ID: W7204265072
FWCI:
Cites: 41
Cited by:
Related to: 10
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