Establishment and Application of a Human Olfactory Epithelial Organoid Biobank
Year: 2026
Type: article
Abstract: In this project, single-cell RNA sequencing (scRNA-seq) technology was utilized to analyze the similarity between the constructed human olfactory epithelial organoids and native human olfactory epithelial tissues at the single-cell level. Furthermore, based on the established human olfactory epithelial organoid platform, a type 2 inflammation model and a SARS-CoV-2 infection model were developed. Through transcriptome sequencing (RNA-seq), key pathogenic genes and signaling pathways in the human olfactory epithelium following inflammatory exposure and SARS-CoV-2 infection were analyzed.
Source: China National GeneBank DataBase
DOI: 10.26036/cnp0009827
Author: 刘金霞
Language: English
Subfield: Sensory Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7204269361
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