Race, ethnicity, and prior colorectal screening test use in CONFIRM colonoscopy vs fecal immunochemical testing trial participants
Year: 2026
Type: article
Abstract: BACKGROUND: Colorectal cancer (CRC) outcomes vary by race and ethnicity, and screening test use may contribute to this variation. We examined the association of race, ethnicity, and associated factors with CRC screening test use in a setting where financial barriers to screening are mitigated. METHODS: Survey information was gathered from US veteran participants (n = 50 125) when enrolled into a randomized trial comparing screening colonoscopy to annual fecal immunochemical testing in the prevention of CRC mortality. The primary exposures of interest were the participants' self-identified race and ethnicity, with adjustment for variables capturing access to care. Multivariable logistic regression, stratified by site and age, was used to assess the relationship between exposures of interest and prior use of any CRC screening test, prior colonoscopy, and prior fecal occult blood test (including fecal immunochemical testing) use. RESULTS: Screening test use was common (n = 28 330 [56.5%]), with more veterans reporting prior fecal occult blood testing (n = 20 386 [40.7%]) than prior colonoscopy (n = 12 671 [25.3%]). In multivariable analysis, Black participants were more likely (odds ratio [OR] = 1.06, 95% confidence interval [CI] = 1.01 to 1.12) to have had any prior screening relative to White persons, and this finding was driven by more frequent fecal occult blood testing use relative to White persons (OR = 1.16, 95% CI = 1.10 to 1.23). There was no association between Hispanic ethnicity (relative to White persons) on the primary outcomes. CONCLUSIONS: In this cohort, prior screening test use was common, with observed variation in overall test use by race, but not ethnicity. Further study of CRC screening test use in diverse populations is needed. CLINICALTRIALS.GOV ID: NCT#05612347 (https://clinicaltrials.gov/study/NCT05612347).
Source: JNCI Cancer Spectrum
Authors: Douglas J Robertson, Jason A Dominitz, Alexander Beed, Kathy Boardman, Barbara J Del Curto, Peter D Guarino, Grant D Huang, Thomas F Imperiale, Andrew LaCasse, Meaghan Larson, Samir Gupta, David Lieberman, Beata Planeta, Timothy J O’Leary, Aasma Shaukat, Shanaz Sultan, Tassos C Kyriakides, CONFIRM Study Group, Ioannis Anastasiou, Fadi Antaki, Gyorgy Baffy, Divya Bhatt, Kerry Brandt Dunbar, Jill Elwing, Paul Feldman, Ronald S Fernando, Deborah A Fisher, Andrew J Gawron, Jeffrey A Gill, Stephan Goebel, Susan F Goldsmith, Katarina B Greer, Ildiko Halasz, Minh Q Ho, Nancy Ho, Samuel B Ho, Mazen Jamal, Charles J Kahi, Andrew M Kaz, Natalia Khalaf, Margaret F Kinnard, Rachel Koppelman, Kyle P Lehenbauer, John G Lieb, Mohammad Madhoun, Priscilla Magno, Ranjan Mascarenhas, Folasade P May, Stacy B Menees, Andy J Mengshol, Farrukh Merchant, Jed Olson, Endashaw Omer, Dipendra Parajuli, Swati G Patel, Emily C Paulson, Marcos Pedrosa, Hugo L Pinillos, Joseph R Pisegna, Heiko Pohl, Devang Prajapati, Kittichai Promrat, Petr Protiva, Divyanshoo Rai Kohli, Rajarajeshwari Ramachandran, Adnan Said, Sameer D Saini, Phillip Schoenfeld, Mitchell Schubert, Tilak Shah, Prateek Sharma, Brian A Sullivan, Dennis H Sullivan, Edward Sun, Alexander M Sy, William M Tierney, Martin Tobi, Claudio Ruben Tombazzi, Doris H Toro, Amelia E Underwood, Erik C Von Rosenvinge, Helen Wong, Michael D Yao, Sonia S Yoon
Institutions: Dartmouth College, White River Junction VA Medical Center, University of Washington, VA Puget Sound Health Care System, VA Connecticut Healthcare System, New Mexico VA Health Care System, Fred Hutch Cancer Center, United States Department of Veterans Affairs, VA Office of Research and Development, Richard L. Roudebush VA Medical Center, Indiana University School of Medicine, University of California San Diego, VA San Diego Healthcare System, Oregon Health & Science University, Portland VA Medical Center, VA NY Harbor Healthcare System, NYU Langone Health, New York University, University of Minnesota, Minneapolis VA Health Care System
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,050
OpenAlex ID: W7204278458
FWCI:
Cites:
Cited by:
Related to: