Work

Upper tract urothelial carcinoma arising in a horseshoe kidney with ureteropelvic junction obstruction: a case report

Year: 2026

Type: article

Abstract: Horseshoe kidney (HSK) is frequently associated with ureteropelvic junction obstruction (UPJO), but the occurrence of upper tract urothelial carcinoma (UTUC) in this setting is exceptionally rare. We report a 66-year-old man presenting with left flank pain and a giant hydronephrotic moiety of an HSK caused by longstanding UPJO. Computed tomography revealed massive hydronephrosis (50 × 46 × 28 cm) with enhancing urothelial wall thickening suspicious for UTUC. The patient underwent open heminephroureterectomy. Histopathology confirmed UTUC. This case highlights the need to suspect malignancy in chronically obstructed horseshoe kidneys and emphasizes the importance of meticulous preoperative imaging and surgical planning.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2026.103589

Authors: Ahmed Chaabouni, Wafa Elleuch, Kays Chaker, Houcine Bouchaala, Yassine Nouira, Mourad Hadj Slimen

Institutions: Hopital Universitaire Habib Bourguiba, University of Sfax, Faculty of Medicine of Sfax, Hôpital La Rabta

Language: English

Topic: Bladder and Urothelial Cancer Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160