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Child Neurology: Radiologic Evolution and Developmental Correlates in Fetal Cerebral Sinovenous Thrombosis

Year: 2026

Type: article

Abstract: Fetal cerebral sinovenous thrombosis (CSVT) is a rare cerebrovascular disorder. We report the neuroimaging evolution and clinical trajectory of 2 children with CSVT detected on fetal MRI. Serial imaging demonstrated that cerebrovascular pathology identified in utero evolved including changes in thrombus burden, venous drainage patterns, and parenchymal sequelae highlighting the importance of structured neuroimaging follow-up. Neurodevelopmental outcomes were associated with the extent of parenchymal injury rather than with persistent sinus occlusion alone. Antenatal identification of CSVT allows for anticipatory counselling, multidisciplinary care planning, early developmental surveillance, and intervention.

Source: Neurology

DOI: 10.1212/wnl.0000000000218524

Authors: Khushboo Kanwal, Roxana Azma, Dawn Gano, Elke Roland, Thiviya Selvanathan

Institutions: University of British Columbia, B.C. Women's Hospital & Health Centre, BC Children's Hospital Research Institute, BC Children's Hospital, University of California, San Francisco, Hospital for Sick Children

Language: English

Topic: Cerebral Venous Sinus Thrombosis

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W7204456957

FWCI:

Cites: 13

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