The Impact of Trauma-Focused Cognitive Behavior Therapy for Psychosis on Post-Traumatic Stress Symptoms in Daily Life: Experience Sampling Methodology Outcomes of the STAR Trial
Year: 2026
Type: article
Abstract: INTRODUCTION: People with psychosis have high rates of post-traumatic stress disorder (PTSD). The Study of Trauma And Recovery (STAR) randomized controlled trial found that a trauma-focused cognitive behavior therapy for psychosis (TF-CBTp) added to treatment-as-usual (TAU) reduced PTSD symptoms in people with psychosis compared to TAU only. We hypothesized that TF-CBTp would also reduce PTSD symptoms in daily life, using experience sampling methodology (ESM), which would be associated with improvements on a clinical measure of PTSD. METHODS: Participants were adults with PTSD and schizophrenia spectrum diagnoses, a subsample of the STAR trial (N = 153; TF-CBTp+TAU = 73, TAU = 80). Participants completed ESM assessments of intrusive memories, hyperarousal, dissociation, avoidance, and negative trauma-related cognitions through a smartphone app multiple times daily over 6 days, at baseline and 9 months post-randomization (end of therapy). RESULTS: No between-group differences were found in ESM measures of momentary PTSD symptoms at 9 months. Significant timepoint × therapy interactions indicated greater decrease over time in hyperarousal, negative cognitions, and avoidance, and in variability of intrusive memories, in TF-CBTp+TAU compared to TAU. ESM measures at 9 months were significantly associated with improvements on the Clinician-Administered PTSD Scale for DSM-5. CONCLUSION: While findings are tentatively in favor of TF-CBTp, the robust reductions in PTSD symptoms found in the STAR trial using retrospective outcome measures were not fully replicated with ESM, suggesting these methodologies may be capturing different features of symptom expression and processes of therapeutic change. Including both approaches in future research could provide a fuller picture of therapy effects on "in-the-moment" versus reflective reports of experiences.
Source: Psychotherapy and Psychosomatics
DOI: 10.1159/pps/aemag010
Institutions: Manchester Academic Health Science Centre, King's College London, South London and Maudsley NHS Foundation Trust, University of Sheffield, Oxford Health NHS Foundation Trust, University of Oxford, Cumbria Northumberland Tyne and Wear NHS Foundation Trust, University of York, KU Leuven, Greater Manchester Mental Health NHS Foundation Trust
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
OpenAlex ID: W7204514640
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