Genome-wide meQTL mapping reveals genetic control of DNA methylation in colon cancer
Year: 2026
Type: article
Study design: Observational Study
Abstract: Methylation quantitative trait loci (meQTLs) are essential for understanding the role of DNA methylation in the genetic susceptibility to colorectal cancer (CRC). However, studies of meQTLs in East Asians and at single base-pair resolution are relatively scarce. We conducted multi-omics analysis using the whole-genome bisulfite sequencing and RNA sequencing in colon cancer samples from 250 Chinese individuals, including methylome and transcriptome correlations (eQTMs) and genetic regulation in cis (meQTLs and eQTLs).
Source: China National GeneBank DataBase
DOI: 10.26036/cnp0008089
Author: 候浩(Hou hao)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7204554780
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