Work

Proof-of-Concept Study of Hyperpolarized [1- 13 C]Pyruvate MRI in Participants with Hepatocellular Carcinoma

Year: 2026

Type: article

Abstract: Hyperpolarized [1- 13 C]pyruvate MRI enabled noninvasive metabolic characterization of focal liver lesions, and alanine-indexed metrics emerged as biological markers of progression to hepatocellular carcinoma beyond CT/MRI–based Liver Imaging Reporting and Data System categorization.

Source: Radiology Imaging Cancer

DOI: 10.1148/rycan.250784

Authors: Uffe Kjærgaard, Nikolaj Bøgh, Malene Aastrup, Mattias Hedegaard Kristensen, Nichlas Vous Christensen, Kim Sivesgaard, Steffen Ringgaard, Lotte Bonde Bertelsen, Esben Søvsø Szocska Hansen, Henning Grønbæk, Gerda Elisabeth Villadsen, Christoffer Laustsen

Institutions: Aarhus University, Aarhus University Hospital, Regional Hospital Horsens, University of Cambridge

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Aarhus Universitet, Institut for Klinisk Medicin, Aarhus Universitet, Danish Cancer Society Research Center

Award: G2036196858

OpenAlex ID: W7204556295

FWCI:

Cites: 31

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