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A Review on Green Hplc Method Development for Dissolution Profiling of Pharmaceutical Drugs

Year: 2026

Type: article

Abstract: The development of Green High-Performance Liquid Chromatography (Green HPLC) offers the prospect of an environmentally sustainable method of pharmaceutical analysis. Traditional HPLC techniques have been associated with the use of harmful organic solvents and production of large amounts of chemical waste, which have caused many environmental and health hazards. Green HPLC, on the other hand, involves minimal usage of solvents, use of environment-friendly solvents, low energy consumption, and efficient analytical technique. Dissolution profiling serves as an important quality assurance test which assesses the release characteristics of pharmaceutical formulations and there in vivo behavior. The use of green HPLC in dissolution studies facilitates the development of pharmaceuticals sustainably without compromising on accuracy, precision, and compliance to regulations.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22159435

Author: *1Sahil, 2Sethi Reeta, 3Singh Sudeep, 4Mehta Rachna

Language: English

Topic: Analytical Methods in Pharmaceuticals

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: green

OpenAlex ID: W7204638457

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