Work

Pairwise Kinship Data Do Not Determine Multi-Way Admixture Diversity: A Group-Theoretic Illustration

Year: 2026

Type: preprint

Abstract: Pairwise kinship data Fst is widely used to measure genetic diversity, but it fails for admixtures of three or more populations. This paper proves why using group theory: two different genetic scenarios can have identical pairwise overlaps but produce different admixture diversities (8 vs 4 in Z2,3). Simulations confirm this limitation. The lesson: use three-population f3-statistics instead of pairwise Fst for accurate admixture detection.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22208456

Author: Amirhossein MoradiSizkouhi

Language: English

Topic: Genetic diversity and population structure

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7204780871

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