Work

Lysosomal Dysfunction–Mediated IgG Accumulation Promotes Endothelial Senescence and Lesion Progression in Cerebral Cavernous Malformations

Year: 2026

Type: preprint

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.64898/2026.08.29.747964

Authors: Yingxi Yang, Yingfan Sun, Shaozhi Zhao, Qiuxia Zhou, Hui Wang, Raymond Sun, Ran Huo, Lan Dao, Zhenhuan Xu, Jiaqi Liu, Rong Grace Zhai, Yiyun Chen, Qi Zhang, Ziyuan Guo, Winson S. Ho, Jiguang Wang, Rongze O. Lu, Yong Cao

Institutions: Capital Medical University, Hong Kong University of Science and Technology, Beijing Tian Tan Hospital, University of California, San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, Cincinnati Children's Hospital Medical Center, University of Chicago, Shenzhen Institutes of Advanced Technology

Language: English

Topic: Vascular Malformations Diagnosis and Treatment

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: National Natural Science Foundation of China

Awards: G3119440009, G5608626781

OpenAlex ID: W7204783430

Cites: 93

Cited by:

Related to: 10