Work

N-[3-(N-tert-Butoxycarbonylaminooxy)propyl]-2-[2-(3-butynylcarbonylamino)ethylthio]-1,3-benzothiazole-6-carboxamide

Year: 2026

Type: article

Abstract: We report the synthesis of a modified benzothiazole sulfide. This compound contains a heterocyclic core, a Boc-protected hydroxylamine, and an appended alkyne. This benzothiazole was accessed through three total steps, including an amidation reaction and two nucleophilic aromatic substitutions. The identity of the title compound was confirmed through 1H, 13C, 1H–1H COSY, HSQC, and HMBC NMR, in addition to IR, MALDI-MS, HRMS, and HPLC.

Source: Molbank

DOI: 10.3390/m2226

Authors: Gabriella G. Meisner, Nora N. Veigas, Christopher R. Shugrue

Institution: University of Richmond

Language: English

Topic: Synthesis and Reactivity of Sulfur-Containing Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $603

Funder: American Chemical Society Petroleum Research Fund