Supplementary Figures S1-S11 from Spatial Mapping of the Precancer-to-Cancer Transition in Breast and Prostate
Year: 2026
Type: supplementary-materials
Abstract: Supplementary Fig. 1. Lightsheet. Supplementary Fig. 2. 3D serial section workflow and motivation. Supplementary Figure 3. Serial section ROIs for HT206B1 (breast). Supplementary Fig. 4. Genes associated with 3D transition ROIs in breast and prostate. Supplementary Fig. 5. Serial section ROIs for HT913Z1 (prostate). Supplementary Fig. 6. 3D proximity of TAMs to non-invasive and invasive epithelial regions in HT704B1. Supplementary Fig. 7. Expression of cohort-level transition genes. Supplementary Fig. 8. Quantification and validation of transition markers. Supplementary Fig. 9. Wound healing assays for MGP and PLAT knockdowns in breast cancer cell lines. Supplementary Fig. 10. Wound healing assays for GDF15, FASN, ALDH1A3, and ANPEP knockdowns in PC-3 prostate cancer cell line. Supplementary Fig. 11. Expression for GDF15, ANPEP, ALDH3A1, and FASN in four prostate cancer cell lines, including PC-3.
Authors: Erik Storrs, Chia-Kuei Mo, Wen-hung Chou, Gaurav Bhatt, Siqi Chen, Xiyi Wei, Andrew Houston, Alla Karpova, Reyka G. Jayasinghe, Preet Lal, Peter Bayguinov, John M. Herndon, Xiang Li, Faria Anjum Simin, Xiangwei Fang, Michael C. Wendl, Xinhao Liu, Hongyu Zheng, Sherri R. Davies, Julia T. Wang, Andrew Shinkle, Robert S. Fulton, Jennifer Ponce, Michael Heinz, Richard Head, De Chen, Yuting Zhao, David Fenyo, Yang E. Li, Cynthia X. Ma, Rebecca Aft, Melissa A. Reimers, Albert H. Kim, Sidharth V. Puram, James A.J. Fitzpatrick, Kooresh I. Shoghi, R. Sherburne Figenshau, Foluso O. Ademuyiwa, Tao Ju, Graham A. Colditz, Bettina F. Drake, Gary J. Patti, Stephen T. Oh, Eric H. Kim, William E. Gillanders, John A. Olson, Milan G. Chheda, Cody Weimholt, Deborah J. Veis, Benjamin J. Raphael, Ryan C. Fields, Russell K. Pachynski, Feng Chen, Li Ding
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W7204901390
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