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Effects of Combined Physical and Cognitive Stimulation on Go/No-Go Performance in Older Women: A Pilot and Feasibility Study

Year: 2026

Type: article

Abstract: This study aimed to examine within-subject changes associated with a 12-week multicomponent training program combined with cognitive stimulation in cognitive–motor performance in older women, and to evaluate changes in cognitive status and health-related quality of life (HRQoL). Thirty-three participants aged 70.24 (4.32) years were assessed at baseline, 6 weeks, and 12 weeks. Cognitive–motor performance was evaluated using a Go/No-Go task, including reaction time (RT), omission errors, and commission errors. Cognitive status was assessed using the Memory, Fluency, and Orientation (MEFO) score, and HRQoL was evaluated with the 36-Item Short Form Health Survey (SF-36). Mixed-effects models showed a significant reduction in RT (Δ = 51.5 ms, p < 0.001; d = 0.50) and omission errors (OR = 0.04, p < 0.001), and an increase in commission errors (OR = 2.06, p = 0.008). Cognitive status improved significantly (Δ = 0.45, p = 0.021; d = 0.34), whereas HRQoL improved only in the general health dimension (Δ = 6.82, p = 0.004; d = 0.53). Overall, the intervention was associated with a reorganization of Go/No-Go performance, characterized by faster responding, but increased commission errors, indicating no improvement in motor inhibition. These findings suggest that this multidomain approach is feasible and warrants evaluation in randomized controlled trials.

Source: Journal of Intelligence

DOI: 10.3390/jintelligence14090205