Supplementary Figure 8 from Intratumoral Sotigalimab with Pembrolizumab Induces Rapid Activation of Antigen-Presenting Cells and Drives Antitumor Responses in Non-injected Tumors in Metastatic Melanoma: A Phase I/II Study
Year: 2026
Type: supplementary-materials
Abstract: Pseudo-time trajectory analysis of CD4+ and CD8+ T cells using scATAC and scRNA data in PBMCs obtained from 3 patients at baseline and after combination therapy (day 3, 8, and 21)
Authors: Salah-Eddine Bentebibel, Daniel J. McGrail, Veena Kochat, Emre Arslan, Reham Abdel-Wahab, Barbara Pazdrak, Ravi Murthy, Nourel Hoda M. Tahon, Sung-Nam Cho, Dzifa Y. Duose, Khalida M. Wani, Jingjing Liu, Cara Haymaker, Javier A. Gomez, Heather Sonnemann, Arjun S. Katailiha, Barbara Nassif-Rausseo, Maha Rahim, Irene Li, Aaron T. Mayer, Xiaodong Yang, Frank J. Hsu, Jianhua Zhang, Daniel H. Johnson, Rodabe N. Amaria, Isabella C. Glitza Oliva, Sapna P. Patel, Patrick Hwu, Khaled M. Elsayes, Hussein A. Tawbi, Jared K. Burks, Chantale Bernatchez, Michael A. Davies, Kunal Rai, Gregory Lizée, Suhendan Ekmekcioglu, Adi Diab
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7204953127
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