Supplementary Figure 8 from Archetype Analysis of Lung Adenocarcinoma Premalignancy Links Heterogeneity in Premalignant Lesions to Diverging Features of Invasive Disease
Year: 2026
Type: supplementary-materials
Abstract: PML archetypes in LUAD cohorts (A-H) Scatterplot of first two principal components computed from GSVA scores for PML-derived modules in LUAD datasets, with annotated projection of PML archetypes (A1-A4) into principal component space. Samples in the top 0.125 proportion of distances from each archetype were assigned archetypes, while other samples were labeled as “secondary”, with colors representing samples in the bin closest to archetype (A) Lung PCA tumor samples (B) Yoo and colleagues tumor samples (C) TRACERx tumor samples (D) GSE68465 tumor samples (E) GSE31210 tumor samples (F) GSE30219 tumor samples (G) TCGA tumor samples (H) Chen and colleagues PML samples.
Authors: Kelley E. Anderson, Linh M. Tran, Kostyantyn Krysan, Yohana Kefella, Lingge Yu, Gregory A. Fishbein, Erika F. Rodriguez, Maryam Shabihkhani, Daniel P. Stefanko, Emily Green, Gang Liu, Hanqiao Liu, Sherry Zhang, Erin Kane, Mitra Mehrad, Avrum E. Spira, Steven M. Dubinett, Eric J. Burks, Sarah A. Mazzilli, Marc E. Lenburg, Jennifer E. Beane
Topic: Lung Cancer Research Studies
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7204999779
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