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Figure S1 from MRTX1133 Suppresses ERK Signaling but Elicits Context-Dependent Antiproliferative Responses in KRAS (G12C) Cancer Cells

Year: 2026

Type: other

Abstract: Binding pose of docked MRTX1133 with KRAS (G12D) aligned with a reference structure (PDB 7RPZ).

DOI: 10.1158/1535-7163.33414981

Authors: Abraham C. Sianoya, Yan Zuo, Cynthia V. Pagba, Jacob L. Jakubec, Stephanie A. Planque, Jeffrey A. Frost, Paul Mark B. Medina, Alemayehu A. Gorfe

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7205003435

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