Supplementary Figure 5 from Archetype Analysis of Lung Adenocarcinoma Premalignancy Links Heterogeneity in Premalignant Lesions to Diverging Features of Invasive Disease
Year: 2026
Type: supplementary-materials
Abstract: Shared mutations across histology and archetypes (A) Plot visualizing frequency of single nucleotide mutations in Lung PCA samples. The top bar graph shows the frequency of mutations for each sample. The right bar graph shows the frequency of mutations in each gene Each column represents a sample, and each row corresponds to a different gene previously identified as a cancer driver in studies of LUAD and LUAD PMLs. Sample histology and archetype are annotated in bottom 2 rows. Samples without mutations in these genes (n = 16 samples) not shown.
Authors: Kelley E. Anderson, Linh M. Tran, Kostyantyn Krysan, Yohana Kefella, Lingge Yu, Gregory A. Fishbein, Erika F. Rodriguez, Maryam Shabihkhani, Daniel P. Stefanko, Emily Green, Gang Liu, Hanqiao Liu, Sherry Zhang, Erin Kane, Mitra Mehrad, Avrum E. Spira, Steven M. Dubinett, Eric J. Burks, Sarah A. Mazzilli, Marc E. Lenburg, Jennifer E. Beane
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W7205006989
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