Supplementary Figure 10 from Archetype Analysis of Lung Adenocarcinoma Premalignancy Links Heterogeneity in Premalignant Lesions to Diverging Features of Invasive Disease
Year: 2026
Type: supplementary-materials
Abstract: Association of archetypes with histology and nodule density in an independent cohort of PML Visualization of χ2 residuals from χ2 test of association of archetypes with histology and nodule density in Chen and colleagues PML data. Plot shows contribution of each cell to the test statistic, where circle size is proportional to cell contribution. Positive (red) values specify a positive association between the corresponding row and column variables (A) Histology, where the authors sequenced the invasive portion of MIA lesions separately from the in situ parts of the lesion (p = 0.0011) (B) Nodule density (p = 0.056).
Authors: Kelley E. Anderson, Linh M. Tran, Kostyantyn Krysan, Yohana Kefella, Lingge Yu, Gregory A. Fishbein, Erika F. Rodriguez, Maryam Shabihkhani, Daniel P. Stefanko, Emily Green, Gang Liu, Hanqiao Liu, Sherry Zhang, Erin Kane, Mitra Mehrad, Avrum E. Spira, Steven M. Dubinett, Eric J. Burks, Sarah A. Mazzilli, Marc E. Lenburg, Jennifer E. Beane
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7205008495
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