Supplementary Figure S4 from LY3410738, a Covalent Inhibitor of Mutant IDH1/2, Is Effective in Acute Myeloid Leukemia Preclinical Models
Year: 2026
Type: supplementary-materials
Abstract: In vitro dose-dependent inhibition of 2-HG production and H3K9me2 hypermethylation
Authors: Nathan A. Brooks, Anna Skwarska, Vivian Salama, Mark H. Bender, Lisa Kays, Robin I. DeWalt, Bryan Perria, Deepti Thete, Jason R. Manro, Rachel Cavitt, Rebecca Leon, Sandra Gomez, Raquel Torres, John M. Strelow, Paul Milligan, Kate Newell, Kenneth D. Roth, Jean-Emmanuel Sarry, Steven M. Chan, Danalyn Manglicmot Lagutan, Richard Romero, Stephen Antonysamy, Robert L. Johnson, Xueqian Gong, Renato A. Bauer, Timothy P. Burkholder, Patric J. Hahn, Zoran Rankovic, Serge L. Boulet, Courtney D. DiNardo, Marina Konopleva, Raymond Gilmour
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W7207649092