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高脂肪食はAppNL-F/NL-Fノックインマウスモデルの海馬におけるアルツハイマー病の病態を増悪する

Year: 2021
Type: dissertation
Abstract: Dementia is a syndrome that affects memory, thinking, behavior, and the ability to perform everyday activities (Ninomiya, 2019).Alzheimer's disease (AD) is a major type of neurodegenerative dementia, accounting for more than 70% of all cases (Gale et al., 2018).AD is characterized by two well-known pathological hallmarks in the brain, the aggregation of β amyloid (Aβ) into plaques and the aggregation of hyperphosphorylated tau protein into neurofibrillary tangles (Selkoe, 2000).It has been over 100 years since the
Language: English
Open Access status: green
OpenAlex ID: W7208235082
Cites: 18
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Related to: 10