Year: 2015
Type: dissertation
Abstract: An important muscle adaptation to endurance exercise is the ability to increase mitochondrial density and oxidative enzyme activity.Feeding a long-chain fatty acid (LCFA)-based diet was found to induce an increase in mitochondrial biogenesis in muscles by activating the peroxisome proliferator-activated receptors (PPARs) family of nuclear transcription factors.Long-chain saturated and fatty acids (C16-C20) are natural PPARs ligands.However, it remains unclear whether mitochondrial biogenesis in skeletal muscle is similarly influenced by medium-chain fatty acids (MCFA) and whether these also bind PPARs.Therefore, this study aimed to evaluate the effects of
Author: Ishizawa, Rie
Institutions: Kanazawa University, Nara University of Education
Language: Japanese
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7063674890