Work

Meta-CD: a metagenomic sequencing coverage and depth calculator for target species

Year: 2026

Type: article

Abstract: epth Calculator (Meta-CD) is a convenient, biologist-friendly tool for determining coverage and depth to enhance taxonomic detection, functional profiling, and metagenome-assembled genome (MAG) recovery in metagenomics. It supports experimental design and post-sequencing analysis, modeling how genome size, relative abundance, sequencing depth, and DNA quantity influence detection of target species.

Source: Microbiology Resource Announcements

DOI: 10.1128/mra.00811-26

Authors: Callie Claiborne, Zhe Lyu

Institution: North Carolina State University

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

Funders: U.S. Department of Agriculture, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G3662800826, G6607877010