Work

Genome-scale overexpression screening identifies product tolerance and efflux transport as key determinants of high-level L-tryptophan production in Escherichia coli

Year: 2026

Type: article

Source: Metabolic Engineering

DOI: 10.1016/j.ymben.2026.102547

Authors: Yuchen Jiang, Qiang Zhou, Mengyun Xu, Gang Meng, Chunguang Zhao, Aiying Wei, Zhishan Wang, Huiping Jia, Jie Yang, Jia Liu, Liming Liu

Institution: Jiangnan University

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: closed

Funders: National Natural Science Foundation of China, Key Research and Development Program of Ningxia, Science and Technology Support Program of Jiangsu Province

Awards: G5023855590, G5723599221, G6658704044

OpenAlex ID: W7208722355

FWCI:

Cites: 65

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