Seroprevalence of viral hemorrhagic fevers and arboviral infections among febrile patients in Forest Guinea
Year: 2026
Type: preprint
Study design: Observational Study
Abstract: Between 2017 and 2024, routine diagnostics surveillance in Guinea detected several confirmed viral hemorrhagic fever (VHF) cases among febrile patients. To assess exposure to Lassa virus and other viral pathogens, we conducted a retrospective cross-sectional seroprevalence study in Forest Guinea (Guéckédou and N’Zérékoré). Lassa virus seroprevalence was 56.0% in the Guéckédou study group and 29.8% in the N’Zérékoré study group. Seropositivity increased with age in both study groups, suggesting cumulative exposure. Samples from Guéckédou laboratory were also tested for other pathogens, and antibodies against Marburg virus (5.8%), Zika virus (5.4%) and Crimean-Congo haemorrhagic fever virus (1.2%) were detected.
Source: medRxiv
Authors: Fara Raymond Koundouno, Youssouf Sidibe, Hugo Soubrier, Karifa Kourouma, Soua Koulemou, Tamba Elie Millimouno, Fernand M’Bemba Tolno, Saa Lucien Millimono, Kékoura Ifono, Faya Moriba Kamano, Mamadou Dioulde Barry, Bely Sonomy, Mariame Traore, Kaba Keïta, Mette Hinrichs, Beate Becker-Ziaja, Emily Victoria Nelson, Christine Jacobsen, Anke Thielebein, Lisa Oestereich, Meike Pahlmann, Beatriz Escudero-Pérez, Ralf Krumkamp, Stephan Günther, Moussa Kolié, Kaba Keïta, Sira Hélène Guilavogui, N’Faly Magassouba, Sanaba Boumbaly, Giuditta Annibaldis, Sophie Duraffour
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Bundesministerium für Gesundheit
OpenAlex ID: W7208735333