Work

Tandem Tau and α-Synuclein Seed Amplification Assays Reveal α-Synuclein Copathology Potentiates Tau Seeding in Alzheimer’s Disease

Year: 2026

Type: preprint

Study design: Observational Study

Source: Research Square

DOI: 10.21203/rs.3.rs-10845149/v1

Authors: Claudio Soto, Damian Gorski, Haley Evans, Michelle Pinho, Zaina Rehan, Matthew Perkins, Emile Pinarbasi, Jon Reader, Sami Barmada, Henry Paulson, Sandra Pritzkow

Institutions: The University of Texas Health Science Center at Houston, University of Michigan

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging

Awards: G9000072362, G9000137799, Boston University Alzheimer's Disease Research Center, Production and Distribution of well-characterized polymorphic variants of alpha-synuclein aggregates

OpenAlex ID: W7208756036

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