Year: 2026
Type: article
Abstract: Glioblastoma is the most aggressive and common malignant primary brain tumor among adults. Due to its aggressiveness, GBM entails a short median overall survival and fatal outcomes. Incidence notably increases with age, 50% of patients being diagnosed at the age of 65 or older. Given that cognitive loss is commonly confused with age-related cognitive impairment, delays in diagnosis are frequent. Furthermore, the elderly are a vulnerable group, commonly having poorer functional status, more comorbidities, and reduced tolerance to intensive treatments. Therefore, clinical and therapeutic implications should be considered within a multidisciplinary approach. The aim of the present study was to review the current knowledge on the management of glioblastoma in the elderly population (≥ 65 years).
Institutions: Universidad Pública de Navarra (UPNA), Navarre Institute of Health Research, Navarrabiomed, Hospital Universitario Príncipe de Asturias, Hospital Universitari i Politècnic La Fe, Hospital de Basurto, Hospital Universitario Virgen de las Nieves, Institut Català d'Oncologia, Hospital Universitari de Girona Doctor Josep Trueta, Hospital General Universitario de Ciudad Real, Hospital Universitario Ramón y Cajal
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,690
OpenAlex ID: W7208757301