Work

A Technique for the Generation of Mucosal and Acral Melanoma Cell Lines

Year: 2026

Type: article

Abstract: Mucosal and acral melanomas are rare subtypes of melanoma with unique clinical and biological features. A dearth of well-established and characterized melanoma cell lines that reflect rare subtypes impedes research on these lethal diseases. We present a protocol developed by exploring various combinations of established techniques that we used to generate mucosal and acral cell lines from patient tissues and patient derived xenografts.

Source: Pigment Cell & Melanoma Research

DOI: 10.1111/pcmr.70117

Authors: Ishani Banik, Sugandha Basu, Meng Wang, Austin J. Escobar, Veronica Steri, Juan A. Camara Serrano, Paul Phojanakong, Noel Cruz Pacheco, Katy K. Tsai, Edwin A. Alvarez, Adil Daud, Ivan H. El‐Sayed, Anastasia Samarkina, Joy Xu, Jamie D. Aquino, Min Xiao, Meenhard Herlyn, Iwei Yeh

Institutions: University of California, San Francisco, University of California San Francisco Medical Center, The Wistar Institute

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,000

Funders: National Institutes of Health, National Cancer Institute, U.S. Army Medical Research Acquisition Activity

Awards: G5777971034, G7554916412, Rational Approaches to Melanoma Therapy

OpenAlex ID: W7208826933

FWCI:

Cites: 19

Cited by:

Related to: 10