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Therapy-induced IGF1R signaling as an actionable vulnerability in oncolytic virotherapy

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Year: 2026
Type: article
Source: Molecular Therapy
DOI: 10.1016/j.ymthe.2026.08.032
Authors: Alexandra A. Miller, Tae Jin Lee, Ji Young Yoo
Institutions: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center at Houston
Language: English

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: American Cancer Society, Cancer Prevention and Research Institute of Texas, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke, American Legion
Awards: Impact of Focal Adhesion Kinase (FAK) signaling on oncolytic HSV Therapy, G3120836337, Inducing Senolysis with miRNA-433-3p for Enhanced Viro-immunotherapy in Glioblastoma, IGF1R-targeted oncolytic herpes simplex viral therapy for Glioblastoma
OpenAlex ID: W7208837439
FWCI:
Cites: 7
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