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Life-long management of atrial fibrillation in a patient with hypertrophic obstructive cardiomyopathy following alcohol septal ablation: A10-year follow-up case report

Year: 2026

Type: article

Abstract: Alcohol septal ablation (ASA) is an established septal reduction therapy for patients with drug-refractory hypertrophic obstructive cardiomyopathy (HOCM). However, its impact on the long-term incidence of atrial fibrillation (AF) remains unclear. We report a case of a 68-year-old man with HOCM who underwent successful ASA with an improvement in heart failure (HF) symptoms. Four years later, recurrent AF developed, requiring catheter ablation twice. Subsequently, subarachnoid hemorrhage occurred during anticoagulation therapy. Because of the high thromboembolic and bleeding risks and unsuitable anatomy for percutaneous left atrial appendage (LAA) closure, surgical LAA occlusion was performed. This case highlights the importance of lifelong AF management following successful ASA.

Source: Internal Medicine

DOI: 10.2169/internalmedicine.8114-26

Authors: Keitaro Akita, Yoshihisa Naruse, Makoto Sano, Masahiro Hirano, Yuichiro Maekawa

Institutions: Hamamatsu University School of Medicine, Hamamatsu University

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7211872050

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