Work

Synthesis and crystal structure of N -benzyl-5,6-epoxy-7-oxabicyclo[2.2.1]heptane-2,3-dicarboximide

Year: 2026

Type: article

Abstract: The title compound, C 15 H 13 NO 4 , is an analog of a well-known cytotoxic molecule, canthardin. The compound possesses a 3/5/5/5 contiguous stereo-defined ring network, which features cyclic furan, oxirane and cyclic carboxamide moieties. The flexibility of the N -benzyl unit allows for supramolecular chiral (but racemic) packing in the extended crystal structure. The intermolecular interactions in the crystal are dominated by H...H and O...H van der Waals interactions, as shown by Hirshfeld analysis.

Source: Acta Crystallographica Section E Crystallographic Communications

DOI: 10.1107/s2056989026009205

Authors: Joseph F. DeJesus, Mary Helene Marmande, Bailey N. Baxter, Masakazu Nambo, Cathleen M. Crudden, David C. Forbes

Institutions: Institute of Transformative Bio-Molecules, Nagoya University, University of South Alabama, Queen's University

Language: English

Topic: Crystal structures of chemical compounds

Subfield: Inorganic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $500

Funders: University of South Alabama, Japan Society for the Promotion of Science