ALS-Associated Exitron Splicing Produces UBQLN2 Isoforms with Distinct Properties
Year: 2026
Type: preprint
Source: SSRN Electronic Journal
DOI: 10.2139/ssrn.7435655
Institution: University of Wisconsin–Madison
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: American Heart Association, University of Wisconsin Carbone Cancer Center, Waisman Center, Oxford Nanopore Technologies, National Institutes of Health, National Institute of Mental Health, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1236303967, G4004214011, Regulation of RIF1 alternative splicing and isoform functions in non-homologous end joining repair, G625014357, Genetic analysis of UBQLN2-associated neurodegeneration in frontotemporal dementia, Genetic analysis of UBQLN2-associated neurodegeneration in frontotemporal dementia, Ctr9 as a Predictive Biomarker for EZH2 Inhibitor Sensitivity, FMRP regulation of mitochondria and metabolism in mammalian brain development, UW Comprehensive Cancer Center Support, Interrogate FMRP functions in primate brain development, Waisman Center Intellectual and Developmental Disabilities Research Center, Graduate Training in Molecular and Cellular Pharmacology, Protein arginine methylation in breast cancer
OpenAlex ID: W7211992762