Work

In vitro and in vivo assessment of biomineralized amorphous silica fiber scaffolds for bone tissue engineering

Year: 2026

Type: article

Abstract: subcutaneous implantation elicited minimal immune response and rapid deposition of bone extracellular matrix within 6 weeks. These findings demonstrate that controlled biomineralization enhances the biological and mechanical performance of amorphous silica fiber scaffolds (Silica 3.0), highlighting their promise for bone tissue engineering applications.

Source: iScience

DOI: 10.1016/j.isci.2026.117472

Authors: Hyun S. Kim, Jonathon T. Intravaia, Trevon Graham, Sangamesh G. Kumbar, Syam P. Nukavarapu

Institutions: University of Connecticut, University of Nebraska Medical Center, UConn Health

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,240