Work

Transcriptomic aging during severe infection: reproducibility code

Year: 2026

Type: software

Abstract: Reproducibility code for the manuscript "Immune-cell redistribution explains transcriptomic aging signatures during severe infection." This release contains the analysis workflow for transcriptomic-age estimation with RNAAgeCalc, quanTIseq immune-cell deconvolution through immunedeconv, regression modeling, gene-level analysis with limma, and Hallmark pathway enrichment with fgsea. Public datasets: GSE152641 and GSE196399.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22679540

Author: Pinheiro da Silva, Fabiano

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7212016510

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