Work

ERBB2 Activating Mutations Promote Enhanced Internalization and Activity of Trastuzumab Deruxtecan in HER2-Nonamplified Metastatic Breast Cancer

Year: 2026

Type: article

Study design: Observational Study

Source: Clinical Cancer Research

DOI: 10.1158/1078-0432.ccr-26-0198

Authors: Nicholas Mai, Sharanya Nag, Bo Liu, Wanyi Chen, Atif Ali Hashmi, Sophia Zelizer, Anton Safonov, Sherry Shen, Fresia Pareja, Charlie White, Yuan Chen, Pedram Razavi, Komal Jhaveri, Shanu Modi, Sarat Chandarlapaty, Joshua Z. Drago

Institutions: Memorial Sloan Kettering Cancer Center, Cornell University, Princeton University

Language: English

Topic: HER2/EGFR in Cancer Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Center for Cancer Research, Breast Cancer Research Foundation, Brian Piccolo Cancer Research Fund

Awards: G9000928433, G9000928607, G9000928958

OpenAlex ID: W7212018164

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