Real-Life Performance of the Dermatology Long-Term Life Impact Measure (DLLIM) in Atopic Dermatitis: An International Study of 15,450 Patients
Year: 2026
Type: article
Study design: Observational Study
Abstract: To the Editor, Existing dermatological quality-of-life instruments primarily assess short-term burden and psychosocial distress, leaving a gap in the evaluation of long-term consequences (Ezzedine et al, 2025). The Dermatology Long-Term Life Impact Measure (DLLIM) (Silverberg et al, 2025c) was recently developed to address this need. It is a valid and reliable instrument designed to quantify the enduring effects of chronic skin conditions on life trajectories and decision-making. We report an evaluation of the DLLIM in real-life conditions — to our knowledge previously unreported — within an international cohort of patients with atopic dermatitis (AD), across four distinct disease-course groups.
Authors: Flavia Pretti Aslanian, Bruno Halioua, Jerry Tan, Chaoying Gu, Thomas Luger, Julien Seneschal, Roni Dodiuk-Gad, Roberto Takaoka, Cita Rosita Sigit Prakoeswa, Ann'Laure Demessant-Flavigny, Caroline Le Floc'h, Nabil Kerrouche, Stéphanie Merhand, Wendy Smith Begolka, África Luca de Tena Smith, Shulamit Burstein, Delphine Kerob, Charles Taieb, Charbel Skayem, Abraham Getachew Kelbore, Laurent Misery, Therdpong Tempark, Alexander Stratigos, Martin Steinhoff, Jonathan I. Silverberg
Institutions: Parkside Hospital, Western University, Windsor Clinical Research, Fudan University, Huashan Hospital, University Hospital Münster, Centre National de la Recherche Scientifique, Université de Bordeaux, Centre Hospitalier Universitaire de Bordeaux, Hôpital Saint-André, Immunology from Concept and Experiments to Translation, Technion – Israel Institute of Technology, University of Toronto, Emek Medical Center, Universidade de São Paulo, Hospital Universitário da Universidade de São Paulo, Hospital São Paulo, Universitas Airlangga, National Eczema Association, Hôpital Saint-Louis, Assistance Publique – Hôpitaux de Paris, Wolaita Sodo University, University of KwaZulu-Natal, Chulalongkorn University, King Chulalongkorn Memorial Hospital, National and Kapodistrian University of Athens, Andreas Sygros Hospital, Hamad bin Khalifa University, Weill Cornell Medical College in Qatar, Weill Cornell Medicine, Hamad Medical Corporation, George Washington University
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,800
OpenAlex ID: W7212021278