Work

Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

Year: 2026

Type: article

Abstract: This repository contains the code, workflows, and source files used for the analyses presented in the manuscript. Contents Preprocessing and integration of pediatric lung snRNA-seq datasets Harmony integration and Azimuth annotation workflows Cell proportion analyses Differential gene expression analyses Gene ontology and pathway enrichment analyses Heatmap generation Feature plots and visualization scripts Pseudotime trajectory analyses Molecular clock and senescence-related analyses The repository is organized by figure to facilitate reproducibility and code availability.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.22680989

Authors: Shaikh, Sadiya, Kaur, Gagandeep, Rahman, Irfan

Institution: University of Rochester Medicine

Language: English

Topic: Single-cell and spatial transcriptomics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7212051984

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