A Female-Specific Microglial Redox Program Gates Susceptibility to Obesity
Year: 2026
Type: preprint
Source: SSRN Electronic Journal
DOI: 10.2139/ssrn.7485309
Authors: E Kyriakidou, G Cutugno, G Duranthon, P Gaikwad, E Archontoulaki, J Vergne, C Torrent, E Garbaye, S Lillo, O Kassem, D Jimenez-Blasco, P Zizzari, S James, V Simon, A Coutansais, N Dupuy, T Leste-Lasserre, G Laplagne, M David, J Ezan, F Martins, A Brochard, G Adisurja, B Salin, JA Reisz, G Marsicano, C Quarta, L Groc, UV Nägerl, JP Bolaños, R Rua, A D’Alessandro, A Mourier, C Allard, D Cota, A Nadjar
Institutions: Centre National de la Recherche Scientifique, Université de Bordeaux, Inserm, Institut des Maladies Neurodégénératives, Neurocentre Magendie, Institut de Biochimie et Génétique Cellulaires, Universitätsmedizin Göttingen, Institut Interdisciplinaire de Neuroscience, Aix-Marseille Université, Centre d’Immunologie de Marseille-Luminy, Consejo Superior de Investigaciones Científicas, Universidad de Salamanca, Instituto de Investigación Biomédica de Salamanca, Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable, Instituto de Biología Funcional y Genómica, University of Colorado Anschutz, Institut Universitaire de France
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Funders: Biogen, Groupe Lipides et Nutrition, European Commission, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut Universitaire de France, Université de Bordeaux, HORIZON EUROPE European Research Council
Awards: G1047435273, Early Metabolic Programming Affects Hypothalamus Yielding Eating Disorders, Control of energy balance by incretins via the olfactory bulb, Uncovering the neuro-immune mechanisms driving the memory of obesity, G286281421, G3360056500, Role of the POMC-ventral striatal neurocircuit in the development of diet-induced obesity, G4362960244, G4656594441, Role of early hypothalamic microglial bioenergetic alterations in the sex-dependent heterogeneity of obese phenotypes, Glucose homeostasis alteration implicates a novel hypothalamic inflammatory pathway., Astrocytic metabolism-driven epigenetics at the cornerstone of cognitive aging, G594818701, G5959744682, G6069939831, G7080048889, Role of mitochondrial cannabinoid type 1 receptor in hypothalamic circuits and its interaction with mTORC1 pathway during obesity., G7878646764, France-BioImaging (Biological Imaging Next-Generation Instrument), G996255883
OpenAlex ID: W7212081562